1QR1
POOR BINDING OF A HER-2/NEU EPITOPE (GP2) TO HLA-A2.1 IS DUE TO A LACK OF INTERACTIONS IN THE CENTER OF THE PEPTIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA-A2.1 HEAVY CHAIN | polymer | 275 | 31854.2 | 2 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (human) | |
| 2 | B, E (B, E) | BETA-2 MICROGLOBULIN | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C, F (C, F) | GP2 PEPTIDE | polymer | 9 | 884.1 | 2 | UniProt (P04626) | ||
| 4 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
B, E: 0 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | Ala 11 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 89235.3 | |
| All* | Total formula weight | 89235.3 |
