1QO3

Complex between NK cell receptor Ly49A and its MHC class I ligand H-2Dd

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MHC CLASS I H-2DD HEAVY CHAIN	polymer	277	32265.9	1	UniProt (P01900) Pfam (PF00129) Pfam (PF07654) In PDB	MUS MUSCULUS (MOUSE)	H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-D ALPHA CHAIN, (H-2D(D))
2	B	BETA-2-MICROGLOBULIN	polymer	100	11791.5	1	UniProt (P01887) Pfam (PF07654) In PDB	MUS MUSCULUS (MOUSE)	B2M
3	C, D	LY49A	polymer	137	15921.3	2	UniProt (P20937) Pfam (PF00059) In PDB	MUS MUSCULUS (MOUSE)	NK-CELL SURFACE GLYCOPROTEIN YE1/48, T LYMPHOCYTE ANTIGEN A1, LY49-A ANTIGEN, LY49A
4	P	HIV ENVELOPE GLYCOPROTEIN 120 PEPTIDE	polymer	10	1075.3	1	UniProt (P04582) In PDB	HUMAN IMMUNODEFICIENCY VIRUS
5	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6		water	water		18.0	352	Chemie (HOH)

Sequence modifications

A: 1 - 1 (PDB: 1QO3)
A: 2 - 277 (UniProt: P01900)
B: 0 - 0 (PDB: 1QO3)
B: 1 - 99 (UniProt: P01887)

PDB	External Database	Details
Ala 85	Asp 105	variant

C, D: 126 - 262 (UniProt: P20937)

PDB	External Database	Details
Ser 126	Lys 126	engineered mutation
Thr 166	Ala 166	variant
Arg 223	Gly 223	variant

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	76975.4
Non-Polymers*	Number of molecules	3
	Total formula weight	186.2
All*	Total formula weight	77161.6

*Water molecules are not included.