1QNH
Plasmodium falciparum Cyclophilin (double mutant) complexed with Cyclosporin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | polymer | 170 | 18884.4 | 2 | UniProt (Q25756) Pfam (PF00160) | PLASMODIUM FALCIPARUM | PPIASE, ROTAMASE, CYCLOPHILIN A |
| 2 | C, D (C, D) | CYCLOSPORIN A | polymer | 11 | 1220.6 | 2 | NOR (NOR00033) BIRD (PRD_000142) | TOLYPOCLADIUM INFLATUM | CYCLOSPORINE, CICLOSPORIN, CICLOSPORINE |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 171 (UniProt: Q25756)
| PDB | External Database | Details |
|---|---|---|
| Leu 120 | Phe 120 | engineered mutation |
| Trp 171 | Leu 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 40210.1 | |
| All* | Total formula weight | 40210.1 |
