1QDU
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TRIPEPTIDE KETONE INHIBITOR ZEVD-DCBMK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J, M... (A, C, E, G, I...) | CASPASE-8 ALPHA-CHAIN | polymer | 153 | 17417.0 | 6 | UniProt (Q14790) Pfam (PF00656) | Homo sapiens (human) | |
| 2 | B, E, H, K, N... (B, D, F, H, J...) | CASPASE-8 BETA-CHAIN | polymer | 88 | 10186.6 | 6 | UniProt (Q14790) Pfam (PF00656) | Homo sapiens (human) | |
| 3 | C, F, I, L, O... (T, U, V, W, X...) | PHQ-GLU-VAL-ASP-DICHLOROMETHYLKETONE INHIBITOR | polymer | 5 | 546.4 | 6 | BIRD (PRD_000295) | Z-EVD-DCBMK | |
| 4 | AA, BA, CA, DA, EA... (H, I, J, K, L...) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K: 149 - 299 (UniProt: Q14790)
| PDB | External Database | Details |
|---|---|---|
| His 204 | Asp 285 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 168900.0 | |
| All* | Total formula weight | 168900.0 |
