1QCN

CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	FUMARYLACETOACETATE HYDROLASE	polymer	421	47047.0	2	UniProt (P35505) Pfam (PF09298) Pfam (PF01557)	Mus musculus (house mouse)
2	C, F (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, E, H, I (A, B)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	G (B)	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
5	J, K (A, B)	water	water		18.0	604	Chemie (HOH)

Sequence modifications

A, B: 1 - 419 (UniProt: P35505)

PDB	External Database	Details
Gly -1	-	cloning artifact
Ser 0	-	cloning artifact
Mse 1	Met 1	modified residue
Mse 71	Met 71	modified residue
Mse 115	Met 115	modified residue
Mse 140	Met 140	modified residue
Mse 177	Met 177	modified residue
Mse 180	Met 180	modified residue
Mse 198	Met 198	modified residue
Mse 202	Met 202	modified residue
Mse 228	Met 228	modified residue
Mse 231	Met 231	modified residue
Mse 266	Met 266	modified residue
Mse 270	Met 270	modified residue
Mse 308	Met 308	modified residue
Mse 322	Met 322	modified residue
Mse 326	Met 326	modified residue
Mse 362	Met 362	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94093.9
Non-Polymers*	Number of molecules	7
	Total formula weight	375.0
All*	Total formula weight	94469.0

*Water molecules are not included.