1Q6M
THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-tyrosine phosphatase, non-receptor type 1 | polymer | 310 | 36238.2 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | B (A) | {[2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-2-(3,4-DIFLUOROPHENYL)PROPANE-1,3-DIYL]BIS[4,1-PHENYLENE(DIFLUOROMETHYLENE)]}BIS(PHOSPHONIC ACID) | non-polymer | 685.4 | 1 | Chemie (P27) | |||
| 3 | C (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Met 489 | - | cloning artifact |
| Asp 490 | - | cloning artifact |
| Tyr 491 | - | cloning artifact |
| Lys 492 | - | cloning artifact |
| Asp 493 | - | cloning artifact |
| Asp 494 | - | cloning artifact |
| Asp 495 | - | cloning artifact |
| Asp 496 | - | cloning artifact |
| Lys 497 | - | cloning artifact |
| Leu 498 | - | cloning artifact |
| Glu 499 | - | cloning artifact |
| Phe 500 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36238.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 685.4 | |
| All* | Total formula weight | 36923.6 |
