1Q6J
THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-tyrosine phosphatase, non-receptor type 1 | polymer | 310 | 36238.2 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | B (A) | [4-(2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL](DIFLUORO)METHYLPHOSPHONIC ACID | non-polymer | 649.5 | 1 | Chemie (335) | |||
| 3 | C (A) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Met 1001 | - | cloning artifact |
| Asp 1002 | - | cloning artifact |
| Tyr 1003 | - | cloning artifact |
| Lys 1004 | - | cloning artifact |
| Asp 1005 | - | cloning artifact |
| Asp 1006 | - | cloning artifact |
| Asp 1007 | - | cloning artifact |
| Asp 1008 | - | cloning artifact |
| Lys 1009 | - | cloning artifact |
| Leu 1010 | - | cloning artifact |
| Glu 1011 | - | cloning artifact |
| Phe 1012 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36238.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 649.5 | |
| All* | Total formula weight | 36887.6 |
