1Q68

Solution structure of T-cell surface glycoprotein CD4 and Proto-oncogene tyrosine-protein kinase LCK fragments

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	T-cell surface glycoprotein CD4	polymer	38	4693.6	1	UniProt (P01730) Pfam (PF12104) In PDB	Homo sapiens (human)	T-cell surface antigen T4/Leu-3
2	B	Proto-oncogene tyrosine-protein kinase LCK	polymer	29	3299.6	1	UniProt (P06239) In PDB	Homo sapiens (human)	P56-LCK, LSK, T cell-specific protein-tyrosine kinase
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 396 - 433 (UniProt: P01730)

PDB	External Database	Details
Leu 407	Met 432	engineered mutation

B: 7 - 35 (UniProt: P06239)

PDB	External Database	Details
Leu 14	Met 13	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	7993.2
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	8058.6

*Water molecules are not included.