1Q62
PKA double mutant model of PKB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase, alpha-catalytic subunit | polymer | 350 | 40696.4 | 1 | UniProt (P00517) Pfam (PF00069) | Bos taurus (cattle) | PKA C-alpha |
| 2 | B (I) | cAMP-dependent protein kinase inhibitor, alpha form | polymer | 20 | 2226.4 | 1 | UniProt (P04541) UniProt (by SIFTS) (P61925) | PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform | |
| 3 | C, D (A, I) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 1 - 350 (UniProt: P00517)
| PDB | External Database | Details |
|---|---|---|
| Ala 123 | Val 123 | engineered mutation |
| Met 173 | Leu 173 | engineered mutation |
| Tpo 197 | Thr 197 | modified residue |
| Sep 338 | Ser 338 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42922.8 | |
| All* | Total formula weight | 42922.8 |
