1Q61
PKA triple mutant model of PKB
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | cAMP-dependent protein kinase, alpha-catalytic subunit | polymer | 350 | 40697.4 | 1 | UniProt (P00517) Pfam (PF00069) In PDB | Bos taurus (cattle) | PKA C-alpha |
2 | I | cAMP-dependent protein kinase inhibitor, alpha form | polymer | 20 | 2226.4 | 1 | UniProt (P04541) UniProt (by SIFTS) (P61925) In PDB | PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform | |
3 | A | N-OCTANOYL-N-METHYLGLUCAMINE | non-polymer | 321.4 | 1 | Chemie (MG8) | |||
4 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1 - 350 (UniProt: P00517)
PDB | External Database | Details |
---|---|---|
Ala 123 | Val 123 | engineered mutation |
Met 173 | Leu 173 | engineered mutation |
Lys 181 | Gln 181 | engineered mutation |
Tpo 197 | Thr 197 | modified residue |
Sep 338 | Ser 338 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42923.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 321.4 | |
All* | Total formula weight | 43245.3 |