1Q4G
2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prostaglandin G/H synthase 1 | polymer | 553 | 63724.1 | 2 | GenBank (165844) Pfam (PF03098) UniProt (by SIFTS) (P05979) | Ovis aries (sheep) | Cyclooxygenase -1, COX-1, Prostaglandin-endoperoxide synthase 1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1 |
| 2 | C, F (C, F) | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G07375KG) | |||
| 3 | D, G (D, G) | beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G40894EI) | |||
| 4 | E (E) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42831WZ) | |||
| 5 | H (H) | beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G07860ZO) | |||
| 6 | I, J, K, L, Q... (A, B) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 8 | Chemie (BOG) | |||
| 7 | M, U (A, B) | 2-(1,1'-BIPHENYL-4-YL)PROPANOIC ACID | non-polymer | 226.3 | 2 | Chemie (BFL) PubChem (22810) PubChem (448006) PubChem (10082414) | |||
| 8 | N, V (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 9 | O, P, W, X, Y (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) PubChem (753) | |||
| 10 | AA, Z (B, A) | water | water | 18.0 | 654 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 127448.3 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4167.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 4484.9 | |
| All* | Total formula weight | 136101.0 |
