1Q2S
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E | 5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3' | polymer | 20 | 6449.9 | 1 | synthetic construct | ||
| 2 | F | RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3') | polymer | 20 | 6272.8 | 1 | synthetic construct | ||
| 3 | A, B, C, D | Queuine tRNA-ribosyltransferase | polymer | 386 | 42925.7 | 4 | UniProt (P28720) Pfam (PF01702) In PDB | Zymomonas mobilis | tRNA-guanine transglycosylase, Guanine insertion enzyme |
| 4 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | C | 9-DEAZAGUANINE | non-polymer | 150.1 | 1 | Chemie (9DG) | |||
| 6 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 184425.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 411.8 | |
| All* | Total formula weight | 184837.3 |
