1Q0Q

Crystal structure of DXR in complex with the substrate 1-deoxy-D-xylulose-5-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	1-deoxy-D-xylulose 5-phosphate reductoisomerase	polymer	406	44404.9	2	UniProt (P45568) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288)	Escherichia coli	DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, IspC
2	C, E (A, B)	1-DEOXY-D-XYLULOSE-5-PHOSPHATE	non-polymer		214.1	2	Chemie (DXP)
3	D, F (A, B)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
4	G, H (A, B)	water	water		18.0	639	Chemie (HOH)

Sequence modifications

A, B: 1 - 398 (UniProt: P45568)

PDB	External Database	Details
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88809.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1919.1
All*	Total formula weight	90728.8

*Water molecules are not included.