1Q04
Crystal structure of FGF-1, S50E/V51N
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Heparin-binding growth factor 1 | polymer | 146 | 16743.8 | 2 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | Acidic fibroblast growth factor; FGF-1; HBGF-1; AFGF; Beta-endothelial cell growth factor; ECGF-beta; fibroblast growth factor 1 |
2 | A, B | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
3 | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
Glu 50 | Ser 65 | engineered mutation |
Asn 51 | Val 66 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33487.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 184.1 | |
All* | Total formula weight | 33671.6 |