1Q04
Crystal structure of FGF-1, S50E/V51N
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heparin-binding growth factor 1 | polymer | 146 | 16743.8 | 2 | UniProt (P05230) Pfam (PF00167) | Homo sapiens (human) | Acidic fibroblast growth factor; FGF-1; HBGF-1; AFGF; Beta-endothelial cell growth factor; ECGF-beta; fibroblast growth factor 1 |
| 2 | C, D, E, F (A, B) | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| Glu 50 | Ser 65 | engineered mutation |
| Asn 51 | Val 66 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33487.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 184.1 | |
| All* | Total formula weight | 33671.6 |
