1Q03

Crystal structure of FGF-1, S50G/V51G mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heparin-binding growth factor 1	polymer	146	16614.6	2	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	Acidic fibroblast growth factor; FGF-1; HBGF-1; AFGF; Beta-endothelial cell growth factor; ECGF-beta; fibroblast growth factor 1
2	C, D (A, B)	water	water		18.0	129	Chemie (HOH)

Sequence modifications

A, B: 1 - 137 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Gly 50	Ser 65	engineered mutation
Gly 51	Val 66	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33229.3
All*	Total formula weight	33229.3

*Water molecules are not included.