1PZZ

Crystal structure of FGF-1, V51N mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heparin-binding growth factor 1	polymer	146	16701.7	2	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	Acidic fibroblast growth factor; FGF-1; HBGF-1; AFGF; Beta-endothelial cell growth factor; ECGF-beta; fibroblast growth factor 1
2	C, D, F (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	E (A)	FORMIC ACID	non-polymer		46.0	1	Chemie (FMT)
4	G, H (A, B)	water	water		18.0	175	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Asn 51	Val 66	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33403.4
Non-Polymers*	Number of molecules	4
	Total formula weight	334.2
All*	Total formula weight	33737.7

*Water molecules are not included.