1PY1
Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ADP-ribosylation factor binding protein GGA1 | polymer | 158 | 17958.6 | 4 | UniProt (Q9UJY5) Pfam (PF00790) | Homo sapiens (human) | Golgi-localized, gamma ear-containing, ARF-binding protein 1, Gamma-adaptin related protein 1 |
| 2 | E, F, G, H (E, F, G, H) | Beta-secretase | polymer | 8 | 955.0 | 4 | UniProt (P56817) | Beta-site APP cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme, Aspartyl protease 2, Asp 2, ASP2, Membrane-associated aspartic protease 2, Memapsin-2 | |
| 3 | I, J, K, L, M (A, B, C, D, H) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 157 (UniProt: Q9UJY5)
E, F, G, H: 1 - 8 (UniProt: P56817)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
| Ser 1 | Met 1 | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Sep 5 | Ser 498 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 75654.3 | |
| All* | Total formula weight | 75654.3 |
