1PWL
Crystal structure of human Aldose Reductase complexed with NADP and Minalrestat
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | aldose reductase | polymer | 316 | 35898.3 | 1 | UniProt (P15121) Pfam (PF00248) In PDB | Homo sapiens (human) | |
2 | A | 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE | non-polymer | 449.2 | 1 | Chemie (BFI) | |||
3 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
4 | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35898.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1192.6 | |
All* | Total formula weight | 37090.9 |