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1PVH

Crystal structure of leukemia inhibitory factor in complex with gp130

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CInterleukin-6 receptor beta chainpolymer20123069.92UniProt (P40189)
Pfam (PF09240)
Pfam (PF00041)
In PDB
Homo sapiens (human)IL-6R-beta, Interleukin 6 signal transducer, Membrane glycoprotein 130, GP130, Oncostatin M receptor, CDw130, CD130 antigen
2B, DLeukemia inhibitory factorpolymer16918648.62UniProt (P15018)
Pfam (PF01291)
In PDB
Homo sapiens (human)LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor, MLPLI
3A, DIODIDE IONnon-polymer126.92Chemie (IOD)
4waterwater18.0192Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight83437.0
Non-Polymers*Number of molecules2
Total formula weight253.8
All*Total formula weight83690.8
*Water molecules are not included.

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PDB entries from 2024-05-29

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