1PVH
Crystal structure of leukemia inhibitory factor in complex with gp130
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Interleukin-6 receptor beta chain | polymer | 201 | 23069.9 | 2 | UniProt (P40189) Pfam (PF09240) Pfam (PF00041) | Homo sapiens (human) | IL-6R-beta, Interleukin 6 signal transducer, Membrane glycoprotein 130, GP130, Oncostatin M receptor, CDw130, CD130 antigen |
| 2 | B, D (B, D) | Leukemia inhibitory factor | polymer | 169 | 18648.6 | 2 | UniProt (P15018) Pfam (PF01291) | Homo sapiens (human) | LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor, MLPLI |
| 3 | E, F (A, D) | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83437.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 253.8 | |
| All* | Total formula weight | 83690.8 |
