1PTU
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN TYROSINE PHOSPHATASE 1B | polymer | 321 | 37363.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | |
| 2 | B (B) | PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE | polymer | 7 | 802.7 | 1 | DADEPYL-NH2 | ||
| 3 | C, D (A, B) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Thr 151 | Ser 151 | conflict |
| Ser 215 | Cys 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38166.3 | |
| All* | Total formula weight | 38166.3 |
