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1PTT

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE (AC-DEPYL-NH2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PROTEIN TYROSINE PHOSPHATASE 1Bpolymer32137363.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)
2B
(B)
PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDEpolymer5644.61AC-DEPYL-NH2
Sequence modifications
A: 1 - 321 (UniProt: P18031)
PDBExternal DatabaseDetails
Thr 151Ser 151conflict
Ser 215Cys 215engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38008.2
All*Total formula weight38008.2
*Water molecules are not included.

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PDB entries from 2025-12-24

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