1PN5

NMR structure of the NALP1 Pyrin domain (PYD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	NACHT-, LRR- and PYD-containing protein 2	polymer	159	17680.6	1	UniProt (P06654) UniProt (Q9C000) Pfam (PF01378) Pfam (PF02758)	Homo sapiens (human)	Death effector filament-forming ced-4-like apoptosis protein, Nucleotide-binding domain and caspase recruitment domain, Caspase recruitment domain protein 7

Sequence modifications

A: 2 - 56 (UniProt: P06654)

PDB	External Database	Details
Met 1	-	initiating methionine
Gln 2	Thr 228	engineered mutation
Gly 57	-	SEE REMARK 999
Ser 58	-	SEE REMARK 999
Leu 152	-	expression tag
Glu 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag

A: 59 - 151 (UniProt: Q9C000)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17680.6
All*	Total formula weight	17680.6

*Water molecules are not included.