1PN4
Crystal structure of 2-enoyl-CoA hydratase 2 domain of Candida tropicalis multifunctional enzyme type 2 complexed with (3R)-hydroxydecanoyl-CoA.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Peroxisomal hydratase-dehydrogenase-epimerase | polymer | 280 | 31396.7 | 4 | UniProt (P22414) Pfam (PF22622) Pfam (PF01575) | Candida tropicalis | HDE, MULTIFUNCTIONAL BETA-OXIDATION PROTEIN, MFP |
| 2 | E, G, K (A, B, D) | 3R-HYDROXYDECANOYL-COENZYME A | non-polymer | 937.8 | 3 | Chemie (HDC) | |||
| 3 | F, H, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 280 (UniProt: P22414)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | Glu 627 | engineered mutation |
| Gln 187 | His 813 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 125586.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3061.6 | |
| All* | Total formula weight | 128648.5 |
