1PL2
Crystal structure of human glutathione transferase (GST) A1-1 T68E mutant in complex with decarboxy-glutathione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutathione S-transferase A1 | polymer | 222 | 25714.1 | 2 | UniProt (P08263) Pfam (PF02798) Pfam (PF00043) | Homo sapiens (human) | GTH1, HA SUBUNIT 1, GST-EPSILON, GSTA1-1, GST CLASS-ALPHA |
| 2 | C, E (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D, F (A, B) | N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE | non-polymer | 383.5 | 2 | Chemie (ABY) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 527 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 222 (UniProt: P08263)
| PDB | External Database | Details |
|---|---|---|
| Glu 68 | Thr 67 | engineered mutation |
| Cso 112 | Cys 111 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51428.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 837.8 | |
| All* | Total formula weight | 52266.1 |
