1PKD
THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO-CDK2/CYCLIN A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Cell division protein kinase 2 | polymer | 297 | 33873.2 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | p33 protein kinase |
| 2 | B, D | Cyclin A2 | polymer | 258 | 29624.3 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (human) | Cyclin A |
| 3 | A, C | 7-HYDROXYSTAUROSPORINE | non-polymer | 482.5 | 2 | Chemie (UCN) | |||
| 4 | water | water | 18.0 | 402 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 296 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | cloning artifact |
| Tpo 160 | Thr 160 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 126995.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 965.1 | |
| All* | Total formula weight | 127960.0 |
