1PI5
Structure of N289A mutant of AmpC in complex with SM2, carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Beta-lactamase | polymer | 358 | 39544.9 | 2 | UniProt (P00811) Pfam (PF00144) In PDB | Escherichia coli | Cephalosporinase |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | A, B | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID | non-polymer | 319.1 | 3 | Chemie (SM2) | |||
| 5 | water | water | 18.0 | 1179 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 361 (UniProt: P00811)
| PDB | External Database | Details |
|---|---|---|
| Ala 289 | Asn 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79089.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1130.6 | |
| All* | Total formula weight | 80220.4 |
