1PCA
THREE DIMENSIONAL STRUCTURE OF PORCINE PANCREATIC PROCARBOXYPEPTIDASE A. A COMPARISON OF THE A AND B ZYMOGENS AND THEIR DETERMINANTS FOR INHIBITION AND ACTIVATION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROCARBOXYPEPTIDASE A PCPA | polymer | 403 | 45303.8 | 1 | UniProt (P09954) Pfam (PF02244) Pfam (PF00246) | Sus scrofa (pig) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 4 | D (A) | VALINE | non-polymer | 117.1 | 1 | Chemie (VAL) | |||
| 5 | E (A) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A: 3 - 308 (UniProt: P09954)
| PDB | External Database | Details |
|---|---|---|
| Lys 3 | Ala 16 | conflict |
| Ala 31 | Gln 141 | conflict |
| Arg 40 | Ser 150 | conflict |
| Ser 57 | Asn 167 | conflict |
| Ser 66 | Thr 176 | conflict |
| Ile 74 | Val 184 | conflict |
| Asn 89 | Asp 199 | conflict |
| Asn 93 | Asp 203 | conflict |
| Ser 94 | Pro 204 | conflict |
| Ser 95 | Ala 205 | conflict |
| Ser 102 | Asn 212 | conflict |
| Met 103 | Leu 213 | conflict |
| Asn 114 | Asp 224 | conflict |
| Asp 122 | Glu 232 | conflict |
| Leu 125 | Met 235 | conflict |
| Lys 132 | Arg 242 | conflict |
| Ala 133 | Thr 243 | conflict |
| Leu 137 | Phe 247 | conflict |
| Ser 141 | Val 251 | conflict |
| Ser 143 | Pro 253 | conflict |
| Ser 159 | Asn 269 | conflict |
| Ala 162 | Ser 272 | conflict |
| Tyr 169 | Phe 279 | conflict |
| Thr 180 | Val 290 | conflict |
| Lys 184 | Asn 294 | conflict |
| Asn 185 | Asp 295 | conflict |
| Asn 186 | His 296 | conflict |
| Gln 211 | Glu 321 | conflict |
| Ser 212 | Ala 322 | conflict |
| Ser 217 | Asp 327 | conflict |
| Asn 220 | Asp 330 | conflict |
| Ala 223 | Ser 333 | conflict |
| Lys 231 | Thr 341 | conflict |
| Ser 237 | Lys 347 | conflict |
| Tyr 238 | Phe 348 | conflict |
| Lys 239 | Gln 349 | conflict |
| Val 246 | Thr 356 | conflict |
| Val 254 | Thr 364 | conflict |
| Arg 277 | Tyr 387 | conflict |
| Asn 307 | His 417 | conflict |
| Ser 308 | Pro 418 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45303.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 374.7 | |
| All* | Total formula weight | 45678.5 |
