1P73
Crystal structure of EHV4-TK complexed with TP4A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thymidine kinase | polymer | 334 | 37013.3 | 4 | UniProt (P24425) Pfam (PF00693) | Equid herpesvirus 4 (Equine herpesvirus 4) | |
| 2 | E, F, G, H, J... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 3 | I, N, Q, S (A, B, C, D) | P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE | non-polymer | 807.3 | 4 | Chemie (4TA) | |||
| 4 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 23 - 352 (UniProt: P24425)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | cloning artifact |
| Ser 20 | - | cloning artifact |
| His 21 | - | cloning artifact |
| Met 22 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 148053.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 4286.1 | |
| All* | Total formula weight | 152339.3 |






