1P6A
STRUCTURAL BASIS FOR VARIATION IN ADENOVIRUS AFFINITY FOR THE CELLULAR RECEPTOR CAR (S489Y MUTANT)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Fiber protein | polymer | 185 | 20020.6 | 1 | UniProt (P36711) Pfam (PF00541) In PDB | Human adenovirus A serotype 12 (HAdV-12) | SPIKE, Protein IV |
2 | B | Coxsackievirus and adenovirus receptor | polymer | 124 | 13640.5 | 1 | UniProt (P78310) Pfam (PF07686) In PDB | Homo sapiens (Human) | hCAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR |
Sequence modifications
A: 403 - 587 (UniProt: P36711)
B: 24 - 146 (UniProt: P78310)
PDB | External Database | Details |
---|---|---|
Tyr 489 | Ser 489 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 23 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33661.1 | |
All* | Total formula weight | 33661.1 |