1P69

STRUCTURAL BASIS FOR VARIATION IN ADENOVIRUS AFFINITY FOR THE CELLULAR RECEPTOR CAR (P417S MUTANT)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Fiber protein	polymer	185	19934.4	1	UniProt (P36711) Pfam (PF00541) In PDB	Human adenovirus A serotype 12 (HAdV-12)	SPIKE, Protein IV
2	B	Coxsackievirus and adenovirus receptor	polymer	124	13640.5	1	UniProt (P78310) Pfam (PF07686) In PDB	Homo sapiens (Human)	hCAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR

Sequence modifications

A: 403 - 587 (UniProt: P36711)

PDB	External Database	Details
Ser 417	Pro 417	engineered mutation

B: 24 - 146 (UniProt: P78310)

PDB	External Database	Details
Gly 23	-	cloning artifact

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.