1P63
Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ACIDIC FIBROBLAST GROWTH FACTOR | polymer | 144 | 16410.5 | 2 | UniProt (P05230) Pfam (PF00167) | Homo sapiens (human) | HEPARIN-BINDING GROWTH FACTOR 1; HBGF-1; AFGF; Beta-endothelial cell growth factor; ECGF-beta |
| 2 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | D (B) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| Ile 111 | Leu 126 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32820.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 142.1 | |
| All* | Total formula weight | 32963.0 |
