1P62
Structure of human dCK complexed with gemcitabine and ADP-MG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Deoxycytidine kinase | polymer | 263 | 30834.8 | 1 | UniProt (P27707) Pfam (PF01712) | Mus musculus (house mouse) | dCK |
| 2 | B (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (B) | GEMCITABINE | non-polymer | 263.2 | 1 | Chemie (GEO) | |||
| 5 | E (B) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
B: 1 - 260 (UniProt: P27707)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30834.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 714.7 | |
| All* | Total formula weight | 31549.5 |
