1P62
Structure of human dCK complexed with gemcitabine and ADP-MG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Deoxycytidine kinase | polymer | 263 | 30834.8 | 1 | UniProt (P27707) Pfam (PF01712) | Mus musculus (house mouse) | dCK |
| 2 | B (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 3 | C (B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (B) | GEMCITABINE | non-polymer | 263.2 | 1 | Chemie (GEO) PubChem (3461) PubChem (36689110) PubChem (60750) PubChem (46705350) PubChem (57857437) PubChem (58861243) PubChem (70866599) PubChem (466434) PubChem (466435) PubChem (124199223) PubChem (6093357) PubChem (121427567) PubChem (9943183) PubChem (11054511) PubChem (13922197) PubChem (13922196) PubChem (129055365) PubChem (130323960) PubChem (138480680) PubChem (144625626) | |||
| 5 | E (B) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
B: 1 - 260 (UniProt: P27707)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30834.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 714.7 | |
| All* | Total formula weight | 31549.5 |
