1P4O

Structure of Apo unactivated IGF-1R KInase domain at 1.5A resolution.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Insulin-like growth factor I receptor protein	polymer	322	36657.0	2	UniProt (P08069) Pfam (PF07714)	Homo sapiens (human)	CD221 antigen, IGF1R
2	C, D (A, B)	water	water		18.0	635	Chemie (HOH)

Sequence modifications

A, B: 944 - 1264 (UniProt: P08069)

PDB	External Database	Details
Met 943	-	initiating methionine
Ala 1067	Glu 1097	engineered mutation
Ala 1069	Glu 1099	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73313.9
All*	Total formula weight	73313.9

*Water molecules are not included.