1P2I
Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Trypsinogen, cationic | polymer | 223 | 23324.3 | 1 | UniProt (P00760) Pfam (PF00089) In PDB | Bos taurus (cattle) | Beta-trypsin, Fragment |
| 2 | I | Pancreatic trypsin inhibitor | polymer | 58 | 6437.4 | 1 | UniProt (P00974) Pfam (PF00014) In PDB | Bos taurus (cattle) | Basic protease inhibitor, BPI, BPTI, Aprotinin |
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | I | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
I: 1 - 58 (UniProt: P00974)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | Lys 50 | engineered mutation |
| Leu 52 | Met 87 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29761.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 232.2 | |
| All* | Total formula weight | 29993.9 |
