1P1J

Crystal structure of the 1L-myo-inositol 1-phosphate synthase complexed with NADH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Inositol-3-phosphate synthase	polymer	533	59707.8	2	UniProt (P11986) Pfam (PF07994) Pfam (PF01658)	Saccharomyces cerevisiae (baker's yeast)	1L-myo-inositol 1-phosphate synthase, Myo-inositol-1-phosphate synthase, MI-1-P synthase, IPS
2	C, F (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4) PubChem (1061)
3	D, G (A, B)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	2	Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (11250888) PubChem (12309341) PubChem (94865921) PubChem (94865923) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (124432988) PubChem (12309347) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (146167236) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (162951602) PubChem (174084875)
4	E, H (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL) PubChem (753)
5	I, J (A, B)	water	water		18.0	1068	Chemie (HOH)

Sequence modifications

A, B: 1 - 533 (UniProt: P11986)

PDB	External Database	Details
-	Arg 14	SEE REMARK 999
Val 14	Leu 15	SEE REMARK 999
-	Phe 61	SEE REMARK 999
Leu 60	Glu 62	SEE REMARK 999
-	Ala 100	SEE REMARK 999
Glu 98	Lys 101	SEE REMARK 999
Asn 140	Lys 143	SEE REMARK 999
Asp 141	His 144	SEE REMARK 999
Asn 201	Gln 204	SEE REMARK 999
Pro 444	Ala 447	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119415.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1705.0
All*	Total formula weight	121120.5

*Water molecules are not included.