1OZG
The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetolactate synthase, catabolic | polymer | 566 | 61355.8 | 2 | UniProt (P27696) Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) | Klebsiella pneumoniae | ALS |
| 2 | C, L (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D, M (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, N (A, B) | 2-HYDROXYETHYL DIHYDROTHIACHROME DIPHOSPHATE | non-polymer | 468.4 | 2 | Chemie (HE3) | |||
| 5 | F, G, H, I, J... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 8 | Chemie (PEG) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 612 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 566 (UniProt: P27696)
| PDB | External Database | Details |
|---|---|---|
| Glu 560 | - | expression tag |
| His 561 | - | expression tag |
| His 562 | - | expression tag |
| His 563 | - | expression tag |
| His 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 122711.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2024.2 | |
| All* | Total formula weight | 124735.8 |
