1OX5
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Imidazole glycerol phosphate synthase hisHF | polymer | 555 | 61566.3 | 2 | UniProt (P33734) Pfam (PF00117) Pfam (PF00977) | Saccharomyces cerevisiae (baker's yeast) | HISTIDINE BIOSYNTHESIS BIFUNCTIONAL AMIDOTRANSFERASE; IGP synthase; ImGP synthase; IGPS; glutamine amidotransferase:cyclase |
| 2 | C (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 3 | D, E (A, B) | PHOSPHORIC ACID MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)- 3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL] ESTER | non-polymer | 581.4 | 2 | Chemie (1PR) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 552 (UniProt: P33734)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| His -1 | - | cloning artifact |
| 5cs 83 | Cys 83 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 123132.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1221.4 | |
| All* | Total formula weight | 124354.0 |
