1OX4
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Imidazole glycerol phosphate synthase hisHF | polymer | 555 | 61422.2 | 1 | UniProt (P33734) Pfam (PF00117) Pfam (PF00977) | Saccharomyces cerevisiae (baker's yeast) | HISTIDINE BIOSYNTHESIS BIFUNCTIONAL AMIDOTRANSFERASE; IGP synthase; ImGP synthase; IGPS; glutamine amidotransferase:cyclase |
| 2 | B (B) | Imidazole glycerol phosphate synthase hisHF | polymer | 555 | 61565.3 | 1 | UniProt (P33734) Pfam (PF00117) Pfam (PF00977) | Saccharomyces cerevisiae (baker's yeast) | HISTIDINE BIOSYNTHESIS BIFUNCTIONAL AMIDOTRANSFERASE; IGP synthase; ImGP synthase; IGPS; glutamine amidotransferase:cyclase |
| 3 | C, D, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | E, I (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 5 | F, J (A, B) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 1 - 552 (UniProt: P33734)
B: 1 - 552 (UniProt: P33734)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| His -1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| His -1 | - | cloning artifact |
| Cyd 83 | Cys 83 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 122987.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 853.6 | |
| All* | Total formula weight | 123841.0 |
