1OT5
The 2.4 Angstrom Crystal Structure of Kex2 in complex with a peptidyl-boronic acid inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kexin | polymer | 477 | 52183.5 | 2 | UniProt (P13134) Pfam (PF00082) Pfam (PF01483) | Saccharomyces cerevisiae (baker's yeast) | KEX2 protease, Proteinase YSCF |
| 2 | C, D (C, D) | Ac-Ala-Lys-boroArg N-acetylated boronic acid peptide inhibitor | polymer | 4 | 400.3 | 2 | BIRD (PRD_000411) | ||
| 3 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, K (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | H, I, J, L, M... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 6 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 105167.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 682.9 | |
| All* | Total formula weight | 106699.3 |
