1OO8
CRYSTAL STRUCTURE OF A1PI-PITTSBURGH IN THE NATIVE CONFORMATION
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Alpha-1-antitrypsin precursor | polymer | 394 | 44276.3 | 1 | UniProt (P01009) Pfam (PF00079) In PDB | Homo sapiens (human) | Alpha-1 protease inhibitor, Alpha-1- antiproteinase, PRO0684/PRO2209 |
2 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 1 - 394 (UniProt: P01009)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Leu 51 | Phe 75 | engineered mutation |
Ala 59 | Thr 83 | engineered mutation |
Ala 68 | Thr 92 | engineered mutation |
Gly 70 | Ala 94 | engineered mutation |
Ser 232 | Cys 256 | engineered mutation |
Arg 358 | Met 382 | engineered mutation |
Ile 374 | Met 398 | engineered mutation |
Ala 381 | Ser 405 | engineered mutation |
Arg 387 | Lys 411 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44276.3 | |
All* | Total formula weight | 44276.3 |