1OGU

STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	CELL DIVISION PROTEIN KINASE 2	polymer	302	34354.8	2	UniProt (P24941) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	P33 PROTEIN KINASE
2	B, D (B, D)	CYCLIN A2	polymer	260	29884.6	2	UniProt (P20248) Pfam (PF00134) Pfam (PF02984)	HOMO SAPIENS (HUMAN)	CYCLIN A, CYCLIN A3
3	E, G (A, C)	4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE	non-polymer		370.4	2	Chemie (ST8)
4	F, H (B, D)	MONOTHIOGLYCEROL	non-polymer		108.2	2	Chemie (SGM)
5	I, J, K, L (A, B, C, D)	water	water		18.0	134	Chemie (HOH)

Sequence modifications

A, C: -3 - 0 (PDB: 1OGU)
A, C: 1 - 298 (UniProt: P24941)
B, D: 173 - 173 (PDB: 1OGU)
B, D: 174 - 432 (UniProt: P20248)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	128478.8
Non-Polymers*	Number of molecules	4
	Total formula weight	957.1
All*	Total formula weight	129435.9

*Water molecules are not included.