1O6Z

1.95 A resolution structure of (R207S,R292S) mutant of malate dehydrogenase from the halophilic archaeon Haloarcula marismortui (holo form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	MALATE DEHYDROGENASE	polymer	303	32566.3	4	UniProt (Q07841) Pfam (PF00056) Pfam (PF02866)	HALOARCULA MARISMORTUI	MDH
2	E, F, H, I, K... (A, B, C, D)	CHLORIDE ION	non-polymer		35.5	8	Chemie (CL)
3	G, J, M, P (A, B, C, D)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)
4	Q, R, S, T (A, B, C, D)	water	water		18.0	677	Chemie (HOH)

Sequence modifications

A, B, C, D: 105 - 212 (UniProt: Q07841)

PDB	External Database	Details
Ser 207	Arg 188	engineered mutation

A, B, C, D: 282 - 299 (UniProt: Q07841)

PDB	External Database	Details
Ser 292	Arg 267	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130265.2
Non-Polymers*	Number of molecules	12
	Total formula weight	2937.3
All*	Total formula weight	133202.5

*Water molecules are not included.