1O6L
Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | RAC-BETA SERINE/THREONINE PROTEIN KINASE | polymer | 337 | 39388.9 | 1 | UniProt (P31751) Pfam (PF00069) Pfam (PF00433) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN KINASE AKT-2, PROTEIN KINASE B BETA RAC-PK-BETA, PKB BETA |
2 | C | GLYCOGEN SYNTHASE KINASE-3 BETA | polymer | 10 | 1123.2 | 1 | UniProt (P49841) In PDB | HOMO SAPIENS (HUMAN) | GSK-3 BETA |
3 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 40512.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 616.1 | |
All* | Total formula weight | 41128.1 |