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1O6L

Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARAC-BETA SERINE/THREONINE PROTEIN KINASEpolymer33739388.91UniProt (P31751)
Pfam (PF00069)
Pfam (PF00433)
In PDB
HOMO SAPIENS (HUMAN)PROTEIN KINASE AKT-2, PROTEIN KINASE B BETA RAC-PK-BETA, PKB BETA
2CGLYCOGEN SYNTHASE KINASE-3 BETApolymer101123.21UniProt (P49841)
In PDB
HOMO SAPIENS (HUMAN)GSK-3 BETA
3APHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
4AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
5waterwater18.0415Chemie (HOH)
Sequence modifications
A: 146 - 464 (UniProt: P31751)
A: 465 - 479 (PDB: 1O6L)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40512.1
Non-Polymers*Number of molecules3
Total formula weight616.1
All*Total formula weight41128.1
*Water molecules are not included.

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PDB entries from 2024-07-10

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