1O3P
Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Urokinase-type plasminogen activator | polymer | 23 | 2708.2 | 1 | UniProt (P00749) | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
| 2 | B (B) | Urokinase-type plasminogen activator | polymer | 253 | 28435.4 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
| 3 | C, D (B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 4 | E (B) | 2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-6-(CYCLOPENTYLOXY)BENZENOLATE | non-polymer | 336.4 | 1 | Chemie (655) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
B: 16 - 250 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31143.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 720.6 | |
| All* | Total formula weight | 31864.2 |
