1NYM
Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (CXB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase TEM | polymer | 263 | 28911.9 | 1 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | TEM-1, TEM-2, TEM-3, TEM-4, TEM-5, TEM-6, TEM-8/CAZ-2, TEM-16/CAZ-7, TEM-24/CAZ-6, IRT-4, Penicillinase |
| 2 | B, C, D (A) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 3 | E, F (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | G (A) | [(2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLYLACETYL)AMINO]METHYLBORONIC ACID | non-polymer | 258.1 | 1 | Chemie (CXB) | |||
| 5 | H (A) | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Thr 182 | Met 180 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28911.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 565.3 | |
| All* | Total formula weight | 29477.2 |
