1NXY
Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (SM2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase TEM | polymer | 263 | 28911.9 | 1 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | TEM-1, TEM-2, TEM-3, TEM-4, TEM-5, TEM-6, TEM-8/CAZ-2, TEM-16/CAZ-7, TEM-24/CAZ-6, IRT-4, Penicillinase |
| 2 | B (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | C, D (A) | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID | non-polymer | 319.1 | 2 | Chemie (SM2) | |||
| 4 | E (A) | water | water | 18.0 | 447 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Thr 182 | Met 180 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28911.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 677.4 | |
| All* | Total formula weight | 29589.3 |
