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1NVW

Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(Q, R)
Transforming protein p21/H-RAS-1polymer16618875.22UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)C-H-RAS
2C
(S)
Son of sevenless protein homolog 1polymer48156532.71UniProt (Q07889)
Pfam (PF00618)
Pfam (PF00617)
Homo sapiens (human)SOS-1
3D
(Q)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4E, F, H, I, J...
(Q, R, S)
PHOSPHATE IONnon-polymer95.07Chemie (PO4)
5G
(Q)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
6M, N, O
(Q, R, S)
waterwater18.055Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight94283.1
Non-Polymers*Number of molecules9
Total formula weight1211.3
All*Total formula weight95494.4
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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