1NVW
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (Q, R) | Transforming protein p21/H-RAS-1 | polymer | 166 | 18875.2 | 2 | UniProt (P01112) Pfam (PF00071) | Homo sapiens (human) | C-H-RAS |
2 | C (S) | Son of sevenless protein homolog 1 | polymer | 481 | 56532.7 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) | Homo sapiens (human) | SOS-1 |
3 | D (Q) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | E, F, H, I, J... (Q, R, S) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
5 | G (Q) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
6 | M, N, O (Q, R, S) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 94283.1 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1211.3 | |
All* | Total formula weight | 95494.4 |