1NUF
Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-glutamine glutamyltransferase E | polymer | 692 | 76670.5 | 1 | UniProt (Q08188) Pfam (PF00868) Pfam (PF01841) Pfam (PF00927) | Homo sapiens (human) | TGase E, TGE, TGE, Transglutaminase 3 |
| 2 | B, D, E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 3 | C, H, I, J (A) | BROMIDE ION | non-polymer | 79.9 | 4 | Chemie (BR) | |||
| 4 | G (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | K (A) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A: 1 - 692 (UniProt: Q08188)
| PDB | External Database | Details |
|---|---|---|
| Asp 250 | Asn 251 | SEE REMARK 999 |
| Leu 264 | Phe 265 | engineered mutation |
| Arg 561 | Lys 562 | SEE REMARK 999 |
| Arg 653 | Gly 654 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 76670.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 501.5 | |
| All* | Total formula weight | 77172.0 |
