1NPZ

Crystal structures of Cathepsin S inhibitor complexes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cathepsin S	polymer	217	24021.0	2	UniProt (P25774) Pfam (PF00112)	Homo sapiens (human)
2	C, D (A, B)	N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide	non-polymer		529.7	2	Chemie (C1P)
3	E, F (A, B)	water	water		18.0	175	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48041.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1059.4
All*	Total formula weight	49101.3

*Water molecules are not included.