1NMK
The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase A | polymer | 165 | 18036.5 | 2 | UniProt (P62937) Pfam (PF00160) | Homo sapiens (human) | PPIase, Rotamase, Cyclophilin A, Cyclosporin A-binding protein |
| 2 | C, D (A, B) | (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-DIHYDROXY-3-(3-HYDROXYBEN-ZYL)-18-((E)-3-HYDROXY-1-METHYLPROPENYL)-6-ISOPROPYL-11-METHYL-9-(3-OXO-BUTYL)-19-OXA-1,4,7,25-TETRAAZA-BICYCLO[19.3.1]PENTACOSA-13,15-DIENE-2,5,8,20-TETRAONE | non-polymer | 740.9 | 2 | Chemie (SFM) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36073.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1481.8 | |
| All* | Total formula weight | 37554.8 |
